FUNCTIONAL SKILLS ASSESSMENT
FUNCTIONAL SKILLS ASSESSMENT
Better functional capacity and cognitive performance in clozapine responders compared to non-responders: A cross-sectional study.
Nucifora Jr. et al. Schizophrenia Research (2020)
Schizophrenia Research
Better functional capacity and cognitive performance in clozapine responders compared to non-responders: A cross-sectional study
SUMMARY
In this study, the investigators examined clozapine treated patients and compared cognitive and functional capacity across response status using a validated computerized functional capacity assessment battery, the University of Miami Computer-Based Functional Assessment System (CFAS/FUNSAT). They hypothesized that the clozapine non-responders (UTRS) would be more impaired on cognitive and functional capacity measures than clozapine responders (TRS), since non-responders have had a more adverse course of illness.
They showed that patients who responded to clozapine (TRS) with improvements in symptomology also performed significantly better than clozapine non-responders (UTRS) on simulations of real world tasks and cognitive testing.
