LASSI-L and MRI markers of Mild Cognitive Impairment

LASSI-L and MRI markers of Mild Cognitive Impairment
Recovery from Proactive Semantic Interference in MCI and Normal Aging: Relationship to atrophy in brain regions vulnerable to Alzheimer’s Disease.
Loewenstein et. al J Alzheimers Dis. (2017)
Journal of Alzheimer’s Disease
Recovery from Proactive Semantic Interference in Mild Cognitive Impairment and Normal Aging: Relationship to Atrophy in Brain Regions Vulnerable to Alzheimer's Disease

SUMMARY
This study investigated the association between PSI, recovery from PSI, and reduced MRI volumes in AD signature regions among cognitively impaired and unimpaired older adults.
LASSI-L indices eliciting failure to recover from PSI were more highly associated with more MRI regional biomarkers of AD than other traditional cognitive measures.

