LASSI-L versus other Neuropsychological Measures
LASSI-L versus other Neuropsychological Measures
Individual cognitive and depressive traits associated with maternal versus paternal family history of Late-onset Alzheimer’s disease: Proactive semantic interference versus standard neuropsychological assessments.
Wilson et. al Personalized Medicine in Psychiatry (2018)
Personalized Medicine in Psychiatry
Individual cognitive and depressive traits associated with maternal versus paternal family history of Late-onset Alzheimer’s disease: Proactive semantic interference versus standard neuropsychological assessments
SUMMARY
The main objective of this study was to assess cognitive and depressive manifestations associated with Alzheimer’s disease in middle-aged asymptomatic individuals with maternal versus paternal family history of the disease using standardly used neuropsychological measures and a novel cognitive stress test, the Loewenstein-Acevedo Scale for Semantic Interference and Learning (LASSI-L).
This study highlights the value of semantic interference paradigms in early detection of Alzheimer’s and emphasizes the importance of studying maternal versus paternal transmission of the disease.
