LASSI-L versus other Neuropsychological Measures
LASSI-L versus other Neuropsychological Measures
Comparison between FCSRT and LASSI-L to Detect Early Stage Alzheimer’s Disease.
Matias et. al J Alzheimers Dis. (2018)
Journal of Alzheimer’s Disease
Comparison between FCSRT and LASSI-L to Detect Early Stage Alzheimer's Disease
SUMMARY
The Free and Cued Selective Reminding Test (FCSRT) is the most accurate test for the diagnosis of prodromal Alzheimer’s disease (AD). Recently, a novel cognitive test, the Loewenstein-Acevedo Scale for Semantic Interference and Learning (LASSI-L), has been developed in order to provide an early diagnosis. The objective was to compare the diagnostic accuracy of the FCSRT and the LASSI-L for the diagnosis of AD in its preclinical and prodromal stages using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) as a reference.
The LASSI-L, a cognitive stress test, was superior to FCSRT in the prediction of AD features on FDG-PET. This emphasizes the possibility to advance toward an earlier diagnosis of AD from a clinical perspective.
